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尊龙凯时胃肠胶囊维持胚胎小白鼠胃组织器官型植块存活及促进细胞增殖
[摘要]：目的：通过体外检测尊龙凯时胃肠胶囊（GIC）对胚胎小白鼠胃组织器官型植块生长的影响以探索GIC修复胃肠道粘膜损伤的机理。方法：体外培养胚胎小白鼠胃器官型植块，将植块分为两组：实验组和对照组。结果：实验组的胃器官型植块能很好地维持存活，从其中长出的单个细胞以及细胞克隆生长好、生长时间长。而对照组的胃器官型植块很快变性死亡。二者差异非常显著。结论：GIC能维持胚胎小白鼠胃器官型植块存活并促进来自植块的细胞和细胞克隆的生长，并且此过程可能与GIC激活上皮干细胞有关。
[关键词]：GIC；胃植块；生长
GIC Could Maintain Survival and Promote Cell Growth of Organ-Type
Explants of Stomach of Mouse Embryo Xu rong-xiang,Wang Yan-ping,Fan
Ran,etc。
Central laboratory, MEBO Global Group 100053
[Abstract]： Objective: To research on the reparative mechanism
of GIC on the lesion of gastrointestinal tract through testing the
effect of GIC on survival and growth of organ-type explants of gastric
tissue of mouse embryo. Methods: Cultured the organ-type explants
of gastric tissue of mouse embryo in vitro, all the explants were
divided into two groups: test group and control group. Results:
Explants in test group could survive，single cells and cell clones
from explants grew well and long. However, explants, cells and cell
clones in control group died off after a short period of time. There
was significant difference between two groups. Conclusion: MEBO
could promote survival and growth of cells of gastric explants of
mouse embryo and this process may be related to activation of epithelial
stem cells.
[Key words]： GIC; gastric explant; growth
本实验的目的在于通过体外检测GIC对胚胎小白鼠胃组织器官型植块生长的影响以初步探讨GIC治疗粘膜损伤性疾病的机理。
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